Some species of the Baccharis genus have been shown to possess important biomedical properties, including cytotoxic activity.\nIn this study, we examined the cytotoxic effect of methanol extract from Baccharis obtusifolia (Asteraceae) in cancer cell lines of\nprostate (PC-3), colon (RKO), astrocytoma (D-384), and breast (MCF-7). The methanolic extract displayed the largest substantial\ncytotoxic effect in lines of colon cancer (RKO) and cerebral astrocytoma (D-384). Chromatographic purification of the B.\nobtusifolia methanolic extract led to the isolation and identification of ... dihydroxy ... methoxyflavone (1) and ... hydroxy ... dimethoxyflavone (2) compounds of the flavonoid type.
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